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GLP 1 Agonists for ObesityA New Recipe for Success? Zeina Al Mahayri, Ph.D. GLP 1 agonists and changes in body mass and composition in adults with overweight or obesity with or without type 2 diabetes mellitus: a systematic review and meta analysis International Journal of Obesity GLP 1 based therapies for diabetes, obesity and beyond Nature Reviews Drug Discovery Oral GLP 1 RA lowers Weight and A1c Diabetes Education Services Drugmaker warns copycat GLP 1 drugs pose serious safety risks to patients Fox Business Trump's Plan to Expand Access to Weight Loss Drugs Just Hit a Major Roadblock
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.3 ★★★★★
Based on 2426 reviews
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Product Reviews
★★★★★ 5
Fan For Life!
Size: Gallon
I would not expect this to seal sidewall penetration or save an old tire from dry rot, but when it comes to road surface tire penetration there is absolutely no better or faster way to repair a flat.
1. You don’t have to remove the tire from the vehicle. Losing half a day waiting for a fixed flat tire is at an end!
2. While a bit pricey, it comes out to be a bit cheaper than a shop trip for smaller UTV or mower tires and A LOT cheaper for larger truck and tractor tires. In 2024, we spent over $350 on flats.
3. We have spiny honey locust trees and bushes invading our farm and deal with flats at least once a month, usually more often than that when clearing fence lines and trees or maintaining pastures. Not to mention the aggravating repeated flats on the same tire are gone.
4. The injector is a bit messy, but the residue will wash off in water if it is cleaned before it dries.
5. So far of the six treated tires on various machines, we’ve had no repeat flats or leaks.
6. Red valve covers come with the packaging so it’s easy to see whether a tire has been treated.
7. This works on tubes and no tubed tires.
8. I’ve used this on my truck, SUV, riding mower, UTV, tractor front tires, and backhoe front tires. Works as promised every time.
If the manufacturer is reading this review, I would appreciate a simpler dosing and injection system - especially on the gallon jug. I’m thinking of something like the pump on a lotion bottle where one pump equals one ounce for example. And provide more than one injector hose. Attach a string or other keeper on the valve removal tool. Losing this tiny tool would make the whole system inoperative.
Overall, I’m a lifetime fan.
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Reviewed in the United States on October 9, 2025
★★★★★ 5
Works Awesome
Size: 40oz
Product works great. I have it in my lawn mower tires. I have a property that we cleared of 100's of mesquite trees and I have been getting flats everytime I mowed. I added this to the tires and have now mowed 6 times with no flats. Keep in mind it does not work on tires with tubes but works perfect for tubeless tires. I have ordered 2 more kits for my 4 wheelers.
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Reviewed in the United States on May 27, 2026
★★★★★ 5
10/10
Size: 20oz
Awesome stuff, used it on some very dry rotted law mower tires just to see what it would do. Worked great holding air again
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Reviewed in the United States on May 1, 2026
★★★★★ 5
Works well!
Style: 16 oz
This stuff works well. I've only ever used it after my tires had been punctured and ran flat... I haven't had a flat this wouldn't seal... 3 uses so far all 3 have fixed flats and been many miles put on since the repairs. I start with as little as possible and if it doesn't seal I just add more, I think I've managed to use far less than recommended and successfully sealed punctures. I've only used it on fat tire e-bike tires. I'm pretty comfortable with the seal and I have no plans to replace the tubes, which saves me a fair amount of trouble. I will update if it springs any leaks without new punctures.
It's very easy to use and actually pretty clean especially compared to automotive type tire repair foams.
The first repair I used it for was a brand new bike that just wouldn't hold air in the rear, totally unsure what caused it to keep losing air but 2 or 3 small doses of slime fixed it.
The most recent slime repair, I had a wobbly bike ride which felt weird and I couldn't figure out why but a few hours after I had returned home both tires were totally flat. They both had a handful or more of some really heavy duty thorns stuck in the tire that likely barely punctured the tubes but the rear tire also had a roofing nail in it. I did not think the slime was going to fill that one, it was a pretty heavy leak once I removed the nail, but Slime did seal it and I've since ridden the bike twice and in the same rough conditions I normally would still holding strong at higher pressure than I normally ride, have yet to drop back down since refilling but I am hoping and expecting it won't be a problem.
Two thumbs up. I always keep a small tube in my bike bag and I am confident if I ever need it while I'm out and about it will be useful.
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Reviewed in the United States on May 17, 2026
★★★★★ 5
Who can live without slime great stuff and a good price. 👍
Style: 32 oz
If anyone has an outdoor anything that takes air. You should never be caught without this stuff. It seals your tires on almost anything and it lasts longer than you would expect. It’s easy to use and easy to clean up after using it. It will work well for anything that is supposed to hold air. Great product.
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Reviewed in the United States on April 11, 2026
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