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Prescription Weight Loss Medications: How They Work People who stop using GLP 1s tend to regain much of the lost weight. Two new studies identify strategies that can help stave this off: https: bit.ly 4dgSjS1 Retatrutide, the next generation of GLP 1 drug from Eli Lilly, helped participants lose an average of 71.2 pounds and reduce knee arthritis pain in a late stage clinical trial, the company announced. In Weight loss injections such as GLP 1 agonists (including semaglutide and tirzepatide) are increasingly used but they can affect how some oral medications are absorbed, including contraception and Hormone Replacement Therapy (HRT) New Mapping the effectiveness and risks of GLP 1 receptor agonists Nature Medicine LY3437943, a novel triple glucagon, GIP, and GLP 1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept: Cell Metabolism